SimBiology

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I have seen some similar questions about this but they haven't quite answered what I need to do. For my set-up I have a simple compartmental model which describes drug distribution, the volumes of these compartments is dependent on a parameter ( _Bodyweight_) I am trying to parameterise the model using several datasets which are pooled to provide a single parameter set However each dataset comes from a different experiment where the bodyweights are different and so I cannot use a single set bodyweight for all as it bias' my parameter estimations Does anyone know how I could set a parameter estimation so that for each dataset a different value for the parameter _Bodyweight_ is used?

I have a multi-compartmental PK model that I am trying to parameterise utilising two different data-sets. One data-set is a short term data set (0 -> 24hrs) and the second data set is a single data point at 168 hrs. The only difference between the two is that the initial bolus dosage is a different amount (and so I cannot combine the two sets) How can I get SimBiology to run a parameter estimation where the output parameters are based off of both data sets? I am running MATLAB R2016b on Mac & Version 5.5 of SimBiology

Hi, it is a simple question. I looking at simulating a 1 comp PK model for two groups. These two groups have different dose levels, and we have multiple doses (not just a single dose) for these groups. How can I simulate that? I can't find anywhere where I can add the information about group so that I can define different dose schedules for different groups. I'm using matlab 2012b. Thanks