SimBiology

フォロー

和孝関口 in MATLAB Answers
最後のアクティビティ: 2021 年 12 月 21 日

How to consider steady state concentration of biomarker in Simbiology

I'm trying to develop the QSP model for endogenous biomarker dynamics in the body with simbiology app (R2021). This biomarker remains to be 5 mM in the tissue under untreatment condition, whereas the concentration is gradually increased up to 10 mM and deacreased to 5mM by administrating the some precursor molecules. I would like to fit the parameter for the production and metabolism of this biomarker. How can I set the steady state concentation (in this case; 5mM) in simbiology app?

answers

SimBiology について

A gathering place for scientists working in QSP, PBPK, and PK/PD modeling using SimBiology and MATLAB. Features discussions, shared models and code, and other resources from our global community of users.