SimBiology

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I have three supplements that I would like to compare (bioavailability). For each of the three, we will have whole bood, serum, and urine measurements done at timed intervals in a day. Supplements will be given orally and it will be a single dose (three different days for each). I am exploring the best way to calculate area under the curve using trapezoidal rule, finding tmax, and cmax. I have explored Simbiology and the examples I have seen are far more complex than what I need. I will appreciate any help on getting this done. Thank you.

Hello, I am attempting to calculate AUC of a dimensionless target engagement species (TO_percent). My model maintains dimensions, however the species from which I am calculating AUC is dementionless I set the new AUC species (AUC_TO_percent) to dimensionless*day, and the reaction rate is TO_percent I've attached the following error Note: I am using simbiology 2022b. Any help would be greatly appreciated, thanks so much Brett

I can't seem to find the answer to my question in SimBiology's documentation. Does anyone know how Matlab calculates the non-compartmental AUC? Does it use the linear / log-linear trapezoidal rule? How many points does it use to extrapolate the curve to infinity? Does it use log or linear extension? Many thanks!