![](https://www.mathworks.com/matlabcentral/answers/uploaded_files/293187/image.png)
Dosing in sbiofit example
1 回表示 (過去 30 日間)
古いコメントを表示
Hi,
In the example "Fit a One-Compartment Model to an Individual's PK Profile" for the function sbiofit (the example is found in the sbiofit help page), an initial dose of 10 milligram is used:
dose = sbiodose('dose');
dose.TargetName = 'Drug_Central';
dose.StartTime = 0;
dose.Amount = 10;
dose.AmountUnits = 'milligram';
dose.TimeUnits = 'hour';
I just wonder where that value is coming from as it seems I cannot find it anywhere in the example. Should it be also a value that needs to be estimated, or it is a value that needs to be known from experimental/synthetic data?
Many thanks,
Jacopo
0 件のコメント
採用された回答
Jeremy Huard
2020 年 5 月 15 日
Hi Jacopo,
this is the dose amount used to generate the synthetic data used in this example.
But you are right, it should have been stated in the 'Background' section.
Another option to specify dosing is to include a dose column in the dataset. This gives you the flexibility to specify different dosing schedules and amounts for each group in your dataset.
You can see how doses are created from a dataset programmatically by generating MATLAB code from the Fit Program (it uses createDose() ):
![](https://www.mathworks.com/matlabcentral/answers/uploaded_files/293187/image.png)
Best regards,
Jérémy
0 件のコメント
その他の回答 (0 件)
コミュニティ
その他の回答 SimBiology コミュニティ
参考
カテゴリ
Help Center および File Exchange で Nonlinear Regression についてさらに検索
Community Treasure Hunt
Find the treasures in MATLAB Central and discover how the community can help you!
Start Hunting!