How to replace small section of image with other values within the image?

Hi,

I have a small artifact within my tissue image that I would like to replace with values from the surrounding tissue. However, I do not want a uniform region to replace the artifact. So far I have the code below, which gives me the following image. However, as you can see that it does not line up for replacing the values. I am confused on what to do, I have tried image segmentation but have not got any further either. Any help would be greatly appreciated!

The first half of the code can be ignored, as I am trying to open up multiple files.

clear all

ROI = [ 1350 1550 750 950];
%A=input('type in pixel value for artifact');

for k = 1:100
  fileName = sprintf('paganin_000100.png', k);
  if isfile(fileName)
        % If the file exists, display it.
        imageData = imread(fileName);
        %crop
        imageData = imageData(ROI(1):ROI(2),ROI(3):ROI(4));
        %imshow(imageData);
        imageMatrix(:,:,k) = imageData;
  else
      % Print alert for those files that don't exist.
      fprintf('File not found: "%s".\n', fileName)
  end
end

grayImage = imageData;

I = grayImage;

Rv = [54:154; 67:167; 41:141; 80:180]; % Row Start Matrix
                                              % Column Vector
Rc = 0:15;                                                  % Row Subscript Address Length
Cv=16:116

 
for k=1:100, 
    j=100      
    I(Rv(1,k)+Rc,Cv(j)) = I(Rv(3,k)+Rc, Cv(j));
    I(Rv(2,k)+Rc,Cv(j)) = I(Rv(4,k)+Rc, Cv(j));
end


imshow(I)

Answer 1

[Image Analyst]

Try regionfill() to "smear in" the surrounding vaules to the inside of the region.

[Anon]

c = [131 136 2 12];
r = [108 126 75 56];
BW = roipoly(I,c,r);
imshow(I)
figure
imshow(BW)
J=regionfill(I,BW)
imshow(J)

I have tried this but it does not do what I would like as the metal wire is still present there

[Image Analyst]

Try making your BW mask larger.