How to manage NaN in matrix during imwarp/fitgeotrans

I have a matrix that contains NaN. What is the best way to perform imwarp/fitgeotrans or imrotate operations on the matrix without changing the mean value of the elements of the matrix?

[KALYAN ACHARJYA]

mean or mean2?

How do you find mean of matrix which having NaN elements? It Normally gives NaN

A =
    16     2     3    13
     5   NaN    10     8
     9     7     6    12
     4    14    15     1
>> original_mean=mean2(A)
original_mean =
   NaN