I was struggling with intregation tolerance errors with a pulsed dose in my model and I can't figure out the cause. sbproj file attached

My model is a miRNA dosage model to reduce collagen buildup in the heart and there are random fluctuations from negative values to positive. I'm not sure if this is the cause but my model for this pulsed dose only isn't functioning while the other ones are which is confusing to me.

[Torsten]

So you have a stochastic function that you try to integrate ? This is not possible with usual numerical integration methods.