Build mechanistic systems biology models or PK/PD models
|Construct model object
|Return SimBiology root object
|Delete all model objects
|Search for objects with specified constraints
|Compare SimBiology models and diagram information (Since R2022a)
|Get model components associated with SimBiology model comparison results (Since R2022a)
|Visualize SimBiology model comparison results (Since R2022a)
|Create compartment object
|Add compartment to
|Add observable object to SimBiology model (Since R2020a)
|Create species object and add to compartment object within model object
|Create parameter object and add to model or kinetic law object
|Create reaction object and add to model object
|Create rule object and add to model object
|Add event object to model object
|Construct SimBiology model from
|Model and component information
|Object containing expression for post-simulation calculations (Since R2020a)
|Object containing compartment information
|Object containing species information
|Parameter and scope information
|Object containing model reaction information
|Kinetic law information for reaction
|Hold rule for species and parameters
|Store SimBiology event information
|Hold models, unit libraries, and abstract kinetic law libraries
|Results of comparison between two SimBiology models and diagrams (Since R2022a)
- Create Model of Receptor-Ligand Kinetics
Create and simulate a simple receptor-ligand kinetics model using SimBiology apps.
- Incorporate SGLT2 Inhibition into Physiologically Based Glucose-Insulin Model Using SimBiology Model Builder
Update a glucose-insulin model to integrate sodium-glucose co-transporter 2 (SGLT2) receptor inhibition by a hypothetical compound.
- Construct a Simple Model
This example shows how to construct a simple model programmatically.
- Compare SimBiology Models
Compare any two SimBiology models to find out the differences between them.
- Model a Gene-Regulation Pathway
This example shows how to construct a simple gene-regulation model and simulate it.
- Create and Simulate a Model with a Custom Function
This example shows how to create a custom function and incorporate it in model simulation.
- Define Reaction Rates with Mass Action Kinetics
Use mass action kinetics to define zero-order, first-order, second-order, and reversible reactions.
- Define Reaction Rates with Enzyme Kinetics
Use differential equations, mass action kinetics, or Michaelis-Menten kinetics to define enzyme reactions.
- Events in SimBiology Models
In SimBiology, an event is a discrete transition in value of a quantity or expression in a model.
- Create Pharmacokinetic Models
SimBiology lets you create one-, two-, or multi-compartment pharmacokinetic models for model simulation and parameter estimation.
- What is a SimBiology Model?
A SimBiology model is a dynamic system described by a set of quantities and mathematical expressions.
- Species Object
species objectrepresents a species, which is the amount of a chemical or entity that participates in reactions.
- Doses in SimBiology Models
Use doses to model different dosing regimens.
- Variants in SimBiology Models
Use variants to store alternate parameter values and initial conditions of a model.
- Definitions and Evaluations of Rules in SimBiology Models
Rules are mathematical expressions that allow you to define or modify model quantities, namely compartment capacity, species amount, or parameter value.
- Definitions and Evaluations of Reactions in SimBiology Models
A reaction is a mathematical expression that describe a transformation, transport, or binding process that changes one or more species.
- SimBiology Model Matching Policy
SimBiology uses certain criteria and rules to compare models.