dose_response

Function to fit a dose-response data to a 4 parameter dose-response curve.

% Requirements: nlinfit function in the Statistics Toolbox
% and accompanying m.files: init_coeffs.m and sigmoid.m
% Inputs: 1. a 1 dimensional array of drug concentrations
% 2. the corresponding m x n array of responses
% Algorithm: generate a set of initial coefficients including the Hill
% coefficient
% fit the data to the 4 parameter dose-response curve using
% nonlinear least squares
% Output: a matrix of the 4 parameters
% results[m,1]=min
% results[m,2]=max
% results[m,3]=ec50
% results[m,4]=Hill coefficient
%
% Copyright 2004 Carlos Evangelista
% send comments to [e-mail]
% Version 1.0 01/07/2004