In Simbiology, should the categorical variables be assigned as group variable or covariate in the dataset?
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I am using Simbiology for population pharmacokinetic model development. I use non-linear mixed effect modelling approach. I have a doubt in the intial assignment of data type in the dataset.
Suppose I have age and gender in the dataset. Clearly, I will assign age as covariate. Now gender is also a covariate. But there is a option in the dataset type which is group variable.
Now I am confused on whether I should assign gender as covariate or group variable.?
I am attaching a screenshot for the reference.
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Jeremy Huard
2019 年 6 月 17 日
Group variable defines an index for a subject/experiment. In your dataset, ID is a group variable. Gender and age can be both covariates.
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Praveen Kumar M
2019 年 6 月 17 日
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Jeremy Huard
2019 年 6 月 17 日
It is not necessary to define it as categorical. But covariates require numerical data in SimBiology. In your case, since you have a binary covariate, you could set gender to 1 for female, 0 for male.
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