Saving and Loading the same DICOM image increases its size!

Hello,

I was doing some modifications to a DICOM image using MATLAB, and then I noticed that if I, then, save the modified image, it increases dramatically in size. More importantly, I have also verified that even if I don't do anything to the image, loading and then saving the DICOM image will increase its size (e.g. 90KB to 143KB)?

Any ideas on why this is happening and how can I solve this issue?

[Rik]

Does the original file have a form of compression? Some DICOM programs will export with jpeg compression, but Matlab will generally not.

[Ghady Hajj]

I don't know. I downloaded the files from https://imaging.nci.nih.gov/ncia/login.jsf

[Walter Roberson]

Did you happen to be working with one of the publicly accessible images? Which modality and series was it?

[Ghady Hajj]

The link provided in the previous comment has publicly accessible images. I used MRI and CT images in my code.