Replacing multiple string values

I have a splitted DNA sequence and their counts that is
GUUA 2 (here GUUA is repeated twice)
UUAG 2
UAGC 2
Then I want to replace these strings with other non terminals, that is GUUA by A and UUAG by B, UAGC by C and so on. How is this possible.

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2017 年 6 月 6 日

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2017 年 6 月 6 日

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